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Towards more selective antibiotic inhibitors: a structural view of the complexed binding pocket of E. coli Peptide Deformylase. H. Kirschner, N. Heister, M. Zouatom, T. Zhou, E. Hofmann, J. Scherkenbeck, R. Stoll. J. Med. Chem. 2024, 67, 6384−6396. doi.org/10.1021/acs.jmedchem.3c02382 

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Structural Insights into Antibacterial Payload Release from Gold Nanoparticles Bound to E. coli Peptide Deformylase. H. Kirschner, M. John, T. Zhou, N. Bachmann, A. Schultz, E. Hofmann, J.E. Bandow, J. Scherkenbeck, N. Metzler-Nolte, R. Stoll. ChemMedChem 2023. doi.org/10.1002/cmdc.202300538

97

A Reinvestigation of the Role of the Sorbic Acid Tail on the Antibacterial and Anti-Tuberculosis Properties of Moiramide B. Irina Kollmorgen, Nathalie Bachmann, Michael Dal Molin, Carsten Degenhart, Eldar Zent, Vikram Pareek, Uwe Koch, Jan Rybniker, Nils Metzler-Nolte, Raphael Stoll, Bert Klebl, Julia Elisabeth Bandow, Jürgen Scherkenbeck. ChemMedChem 2023, 18, e202200631.
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96

Synthesis, Biological Evaluation, and Binding Mode of a New Class of Oncogenic K‐Ras4B Inhibitors. Stephan Jeuken, Oleksandr Shkura, Marc Röger, Victoria Brickau, Axel Choidas, Carsten Degenhart, Daniel Gülden, Bert Klebl, Uwe Koch, Raphael Stoll, Jürgen Scherkenbeck. ChemMedChem 2022, 17, e202200392.
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Sequence-Selective Covalent CaaX-Box Receptors Prevent Farnesylation of Oncogenic Ras Proteins and Impact MAPK/PI3 K Signaling. Matthias Franz, Britta Mörchen, Carsten Degenhart, Daniel Gülden, Oleksandr Shkura, Dirk Wolters, Uwe Koch, Bert Klebl, Raphael Stoll, Iris Helfrich, and Jürgen Scherkenbeck. ChemMedChem 2021, 16, 2504-2514.
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